Availability Cascades and Risk Regulation

Modeling RAS-Singaling Cascades and Gene Regulation

Modeling receptor protein regulation and enzyme cascades

Risk Cascades: Anticipating Resilient and Fragile Markets

The global fi nancial crisis of 2008 and the related failure of risk controls put in place after the tech bubble collapse have created a good deal of soul searching in the investment community. This has generated simplistic explanations that either quantitative methods do not work, or conversely that they were applied incorrectly due to the ineptitude and greed of money managers, fund sponsors ...

Overview of Gene Availability, Identification, and Regulation

De Block, M., L. Herrera-Estrella, M. Van Montagu, J. Schell, and P. Zambryski. 1984. Expression of foreign genes in regenerated plants and their progeny. EMBO J. 6:2513–2518. Fraley, R.T., S.G. Rogers, R.B. Horsch, P.R. Sanders, J.S. Flick, S.P. Adams, M.L. Bittner, L.A. Brand, C.L. Fink, J.S. Fry, G.R. Galluppi, S.B. Goldberg, N.L. Hoffman, and S.C. Woo. 1983. Expression of bacterial genes in...

Developmental Cascades Linking Stress Inoculation, Arousal Regulation, and Resilience

Stressful experiences that are challenging but not overwhelming appear to promote the development of arousal regulation and resilience. Variously described in studies of humans as inoculating, steeling, or toughening, the notion that coping with early life stress enhances arousal regulation and resilience is further supported by longitudinal studies of squirrel monkey development. Exposure to e...